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Yuki Fujiwara Selected Research

nafamostat

1/2018Glycogen synthase kinase-3β activity plays a key role in the antitumor effect of nafamostat mesilate in pancreatic cancer cells.
1/2016Dual inhibition of nuclear factor kappa-B and Mdm2 enhance the antitumor effect of radiation therapy for pancreatic cancer.
2/2015Radical Resection of a Primarily Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy Using Gemcitabine, TS-1, and Nafamostat Mesilate; Report of a Case.
9/2013Combination chemotherapy of nafamostat mesylate with gemcitabine for gallbladder cancer targeting nuclear factor-κB activation.
6/2013Combination chemotherapy of serine protease inhibitor nafamostat mesilate with oxaliplatin targeting NF-κB activation for pancreatic cancer.
2/2013Inhibition of nuclear factor kappa-B enhances the antitumor effect of combination treatment with tumor necrosis factor-alpha gene therapy and gemcitabine for pancreatic cancer in mice.
1/2013Inhibition of nuclear factor-κB enhances the antitumor effect of paclitaxel against gastric cancer with peritoneal dissemination in mice.
11/2012Prognostic factors of unresectable pancreatic cancer treated with nafamostat mesilate combined with gemcitabine chemotherapy.
9/2011Nafamostat mesilate can prevent adhesion, invasion and peritoneal dissemination of pancreatic cancer thorough nuclear factor kappa-B inhibition.
7/2011Combination treatment using adenovirus vector-mediated tumor necrosis factor-alpha gene transfer and a NF-κB inhibitor for pancreatic cancer in mice.
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Yuki Fujiwara Research Topics

Disease

38Neoplasms (Cancer)
10/2022 - 09/2009
19Pancreatic Neoplasms (Pancreatic Cancer)
10/2020 - 10/2010
9Neoplasm Metastasis (Metastasis)
01/2021 - 09/2011
6Hepatocellular Carcinoma (Hepatoma)
01/2018 - 09/2009
4Carcinoma (Carcinomatosis)
01/2016 - 11/2012
3Lymphatic Metastasis
01/2021 - 05/2017
3Inflammation (Inflammations)
01/2019 - 09/2016
3Adenocarcinoma
01/2017 - 09/2015
2Carcinogenesis
10/2022 - 07/2016
2Margins of Excision
11/2021 - 01/2021
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2021 - 01/2021
2Ascites
01/2018 - 11/2012
2Pancreatic Fistula (Pancreatic Fistulas)
11/2016 - 01/2015
2Colorectal Neoplasms (Colorectal Cancer)
06/2013 - 04/2012
1Melanoma (Melanoma, Malignant)
10/2022
1Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
06/2022
1Thrombocytopenia (Thrombopenia)
06/2022
1Wilms Tumor (Wilm's Tumor)
04/2022
1Graft vs Host Disease (Graft-Versus-Host Disease)
04/2022
1Hematologic Neoplasms (Hematological Malignancy)
02/2022
1Developmental Disabilities (Developmental Disability)
01/2022
1Pleural Effusion (Pleural Effusions)
01/2021
1Heart Arrest (Cardiac Arrest)
01/2021
1Hemorrhage
01/2021
1Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive)
01/2021
1Bradycardia
01/2021
1Hypoxia (Hypoxemia)
01/2021
1Leukemia
01/2021
1Philadelphia Chromosome
01/2021
1Malignant Pleural Effusion
01/2021
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
09/2020
1Agammaglobulinemia (Hypogammaglobulinemia)
09/2020
1Cytopenia
09/2020
1Type 2 Diabetes Mellitus (MODY)
07/2019
1Multiple Myeloma
12/2018

Drug/Important Bio-Agent (IBA)

12nafamostatIBA
01/2018 - 10/2010
6C-Reactive ProteinIBA
01/2021 - 11/2012
5AlbuminsIBA
01/2021 - 09/2016
5GemcitabineFDA Link
01/2018 - 11/2012
5Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
01/2016 - 10/2010
5AntigensIBA
12/2015 - 04/2012
4Indocyanine Green (Cardio-Green)FDA LinkGeneric
11/2021 - 12/2010
4Pharmaceutical PreparationsIBA
01/2021 - 07/2016
4Indicators and Reagents (Reagents)IBA
01/2018 - 09/2015
4NF-kappa B (NF-kB)IBA
01/2016 - 10/2010
4CarbohydratesIBA
09/2014 - 04/2012
3Monoclonal AntibodiesIBA
01/2021 - 12/2015
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 09/2011
3Interleukin-8 (Interleukin 8)IBA
07/2016 - 09/2011
3Thromboplastin (Tissue Factor)IBA
04/2016 - 09/2015
3Carcinoembryonic AntigenIBA
09/2013 - 04/2012
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2013 - 07/2011
2Rituximab (Mabthera)FDA Link
06/2022 - 09/2020
2Messenger RNA (mRNA)IBA
04/2022 - 01/2021
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
04/2022 - 01/2021
2CytokinesIBA
01/2021 - 03/2016
2Proteins (Proteins, Gene)FDA Link
09/2020 - 12/2017
2Immunoglobulin G (IgG)IBA
09/2020 - 12/2015
2Anti-Bacterial Agents (Antibiotics)IBA
12/2017 - 01/2017
2Paclitaxel (Taxol)FDA LinkGeneric
01/2013 - 05/2011
1Chemokine ReceptorsIBA
10/2022
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
10/2022
1Immune Checkpoint InhibitorsIBA
10/2022
1ChemokinesIBA
10/2022
1obinutuzumabIBA
06/2022
1Bendamustine HydrochlorideFDA Link
06/2022
1Chimeric Antigen ReceptorsIBA
02/2022
1perfluorooctaneIBA
01/2022
1Fetal Proteins (Fetoprotein)IBA
11/2021
1Insulin-Like Growth Factor Binding ProteinsIBA
01/2021
1Alkylating AgentsIBA
01/2021
1Inotuzumab OzogamicinIBA
01/2021
1NicotineFDA Link
01/2021
1blinatumomabIBA
01/2021
1RNA (Ribonucleic Acid)IBA
01/2021
1B7-H1 AntigenIBA
01/2021
1fludarabineIBA
01/2021
1Immunoglobulin IsotypesIBA
09/2020
1Glucagon-Like Peptide 1 (GLP 1)IBA
07/2019
1Peptides (Polypeptides)IBA
12/2018
1pomalidomideIBA
12/2018
1Thalidomide (Thalomid)FDA Link
12/2018
1Glycogen Synthase (Synthase I)IBA
01/2018

Therapy/Procedure

15Therapeutics
10/2022 - 09/2009
11Drug Therapy (Chemotherapy)
06/2022 - 04/2012
9Pancreaticoduodenectomy
01/2019 - 06/2013
6Blood Transfusion (Blood Transfusions)
10/2013 - 09/2009
5Immunotherapy
10/2022 - 03/2016
3Hematopoietic Stem Cell Transplantation
04/2022 - 09/2020
3Neoadjuvant Therapy
10/2020 - 02/2015
3Combination Drug Therapy (Combination Chemotherapy)
09/2013 - 05/2011
2Adjuvant Chemotherapy
10/2017 - 05/2017
2Splenectomy
12/2016 - 01/2014
2Pancreatectomy
12/2016 - 10/2013
2Subcutaneous Injections
09/2013 - 02/2013
1Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
04/2022
1Cell- and Tissue-Based Therapy (Cell Therapy)
02/2022
1Electrocoagulation (Electrocautery)
01/2021
1Salvage Therapy
01/2021
1Argon Plasma Coagulation
01/2021